Ehlers-Danlos Syndrome
Ehlers-Danlos syndrome type II arises because of an abnormality of type V collagen, at least in some individuals. Testing for type V collagen is not so straightforward as that already done for type III collagen. The gene change that results in type II EDS is what is termed autosomal dominant in character. Collagen abnormalities in the various forms of EDS affet the cushioning function of joints. Individuals with various forms of EDS, then, tend to 'wear out' that cushioning function faster tahn average. The joints that are most at risk are weight bearing stress is probably appropriate in an effort to preserve joint function. All collagens require vitamin C as a confactor for their synthesis. Most forms of EDS appear to be caused by underproduction of collagen of one sort or another. Therefore, there is speculation that providing increased confactor may drive the system just a little bit and perhaps diminsh the severity of clinical features 病因學： 為先天 膠原結締組織 異常之遺傳疾病，俗稱...